Target：HoxB5

Gene Name：HOXB5

Protein Name：Homeobox protein Hox-B5

Human Gene Id：3215

Human Swiss Prot No：P09067

Mouse Gene Id：15413

Mouse Swiss Prot No：P09079

Immunogen：The antiserum was produced against synthesized peptide derived from human HoxB5. AA range:150-199

Specificity：HoxB5 Polyclonal Antibody detects endogenous levels of HoxB5 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：HOXB5;HOX2A;Homeobox protein Hox-B5;Homeobox protein HHO.C10;Homeobox protein Hox-2A;Homeobox protein Hu-1

Observed Band(KD)：29kD

Background： This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue. [provided by RefSeq, Jul 2008],

Function：developmental stage:Embryo.,function:Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.,similarity:Belongs to the Antp homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,tissue specificity:Spinal cord.,

Subcellular Location：Nucleus.

Expression：Spinal cord.