Target：HORMAD1

Gene Name：HORMAD1

Protein Name：HORMA domain-containing protein 1

Human Gene Id：84072

Human Swiss Prot No：Q86X24

Mouse Swiss Prot No：Q9D5T7

Immunogen：The antiserum was produced against synthesized peptide derived from human HORMAD1. AA range:321-370

Specificity：HORMAD1 Polyclonal Antibody detects endogenous levels of HORMAD1 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：HORMAD1;NOHMA;HORMA domain-containing protein 1;Cancer/testis antigen 46;CT46;Newborn ovary HORMA protein

Observed Band(KD)：45kD

Background： This gene encodes a HORMA domain-containing protein. HORMA domains are involved in chromatin binding and play a role in cell cycle regulation. The encoded protein may play a role in meiosis, and expression of this gene is a potential marker for cancer. A pseudogene of this gene is located on the long arm of chromosome 6. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010],

Function：similarity:Contains 1 HORMA domain.,tissue specificity:Testis-specific. Over-expressed in carcinomas.,

Subcellular Location：Nucleus . Chromosome . Preferentially localizes to unsynapsed or desynapsed chromosomal regions during the prophase I stage of meiosis. TRIP13 is required for depletion from synapsed chromosomes. The expression of the phosphorylated form at Ser-377 is restricted to unsynapsed chromosomal regions (By similarity). .

Expression：Testis-specific. Over-expressed in carcinomas.