Target：APOBEC3D/F

Fields：Viral life cycle - HIV-1;Human immunodeficiency virus 1 infection

Gene Name：APOBEC3D/APOBEC3F

Protein Name：Probable DNA dC->dU-editing enzyme APOBEC-3D/F

Human Gene Id：200316/140564

Human Swiss Prot No：Q96AK3/Q8IUX4

Immunogen：The antiserum was produced against synthesized peptide derived from human APOBEC3D/F. AA range:232-281

Specificity：APOBEC3D/F Polyclonal Antibody detects endogenous levels of APOBEC3D/F protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：APOBEC3D;Probable DNA dC->dU-editing enzyme APOBEC-3D;APOBEC3F;DNA dC->dU-editing enzyme APOBEC-3F;Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3F

Observed Band(KD)：40kD

Background： This gene is a member of the cytidine deaminase gene family. It is one of a group of related genes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1 and inhibit retroviruses, such as HIV, by deaminating cytosine residues in nascent retroviral cDNA. [provided by RefSeq, Jul 2008],

Function：cofactor:Zinc.,function:Unknown. Unable to reduce HIV-1 infectivity in vitro.,miscellaneous:It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22.,similarity:Belongs to the cytidine and deoxycytidylate deaminase family.,

Subcellular Location：Cytoplasm. Cytoplasm, P-body.

Expression：Expressed in lymphoid organs. Also detected in non-lymphoid tissues including lung.