Target：ACSS1

Fields：Glycolysis / Gluconeogenesis;Pyruvate metabolism;Glyoxylate and dicarboxylate metabolism;Propanoate metabolism;Metabolic pathways;Carbon metabolism

Gene Name：ACSS1

Protein Name：Acetyl-coenzyme A synthetase 2-like mitochondrial

Human Gene Id：84532

Human Swiss Prot No：Q9NUB1

Mouse Gene Id：68738

Mouse Swiss Prot No：Q99NB1

Immunogen：The antiserum was produced against synthesized peptide derived from human ACSS1. AA range:611-660

Specificity：ACSS1 Polyclonal Antibody detects endogenous levels of ACSS1 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：ACSS1;ACAS2L;KIAA1846;Acetyl-coenzyme A synthetase 2-like; mitochondrial;Acetate--CoA ligase 2;Acetyl-CoA synthetase 2;AceCS2;Acyl-CoA synthetase short-chain family member 1

Observed Band(KD)：75kD

Background： This gene encodes a mitochondrial acetyl-CoA synthetase enzyme. A similar protein in mice plays an important role in the tricarboxylic acid cycle by catalyzing the conversion of acetate to acetyl CoA. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011],

Function：catalytic activity:ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA.,function:Converts acetate to acetyl-CoA so that it can be used for oxidation through the tricarboxylic cycle to produce ATP and CO(2).,sequence caution:Sequencing errors.,similarity:Belongs to the ATP-dependent AMP-binding enzyme family.,

Subcellular Location：Mitochondrion matrix .

Expression： Amygdala,Brain,PCR rescued clones,Placenta,Spleen,Stomach,T