Target：Serine racemase

Fields：Glycine, serine and threonine metabolism;D-Amino acid metabolism;Metabolic pathways

Gene Name：SRR

Protein Name：Serine racemase

Human Gene Id：63826

Human Swiss Prot No：Q9GZT4

Mouse Swiss Prot No：Q9QZX7

Immunogen：Synthesized peptide derived from Serine racemase . at AA range: 90-170

Specificity：Serine racemase Polyclonal Antibody detects endogenous levels of Serine racemase protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：SRR;Serine racemase;D-serine ammonia-lyase;D-serine dehydratase;L-serine ammonia-lyase;L-serine dehydratase

Molecular Weight(Da)：37kD

Background：catalytic activity:L-serine = D-serine.,cofactor:Pyridoxal phosphate.,function:Catalyzes the synthesis of D-serine from L-serine.,similarity:Belongs to the serine/threonine dehydratase family.,tissue specificity:Brain: expressed at high levels in hippocampus and corpus callosum, intermediate levels in substantia nigra and caudate, and low levels in amygdala, thalamus, and subthalamic nuclei. Expressed in heart, skeletal muscle, kidney and liver.,

Function：catalytic activity:L-serine = D-serine.,cofactor:Pyridoxal phosphate.,function:Catalyzes the synthesis of D-serine from L-serine.,similarity:Belongs to the serine/threonine dehydratase family.,tissue specificity:Brain: expressed at high levels in hippocampus and corpus callosum, intermediate levels in substantia nigra and caudate, and low levels in amygdala, thalamus, and subthalamic nuclei. Expressed in heart, skeletal muscle, kidney and liver.,

Subcellular Location：cytoplasm,plasma membrane,neuronal cell body,apical part of cell,

Expression：Brain: expressed at high levels in hippocampus and corpus callosum, intermediate levels in substantia nigra and caudate, and low levels in amygdala, thalamus, and subthalamic nuclei. Expressed in heart, skeletal muscle, kidney and liver.