Target：SERGEF

Gene Name：SERGEF

Protein Name：Secretion-regulating guanine nucleotide exchange factor

Human Gene Id：26297

Human Swiss Prot No：Q9UGK8

Mouse Swiss Prot No：Q80YD6

Immunogen：The antiserum was produced against synthesized peptide derived from human SERGEF. AA range:179-228

Specificity：SERGEF Polyclonal Antibody detects endogenous levels of SERGEF protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：SERGEF;DELGEF;GNEFR;Secretion-regulating guanine nucleotide exchange factor;Deafness locus-associated putative guanine nucleotide exchange factor;DelGEF;Guanine nucleotide exchange factor-related protein

Observed Band(KD)：50kD

Background：function:Probable guanine nucleotide exchange factor (GEF), which may be involved in the secretion process.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 7 RCC1 repeats.,subunit:Interacts with SEC5. The interaction occurs only in the presence of magnesium or manganese and is stimulated by dCTP or GTP.,

Function：function:Probable guanine nucleotide exchange factor (GEF), which may be involved in the secretion process.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 7 RCC1 repeats.,subunit:Interacts with SEC5. The interaction occurs only in the presence of magnesium or manganese and is stimulated by dCTP or GTP.,

Subcellular Location：Cytoplasm . Nucleus .

Expression： Fetal brain,Ovary,