Target：HGFA
Gene Name：HGFAC
Protein Name：Hepatocyte growth factor activator
Human Gene Id：3083
Human Swiss Prot No：Q04756
Mouse Gene Id：54426
Mouse Swiss Prot No：Q9R098
Immunogen：Synthesized peptide derived from the C-terminal region of human HGFA.
Specificity：HGFA Polyclonal Antibody detects endogenous levels of HGFA protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：HGFAC;Hepatocyte growth factor activator;HGF activator;HGFA
Observed Band(KD)：70kD
Background： This gene encodes a member of the peptidase S1 protein family. The encoded protein is first synthesized as an inactive single-chain precursor before being activated to a heterodimeric form by endoproteolytic processing. It acts as serine protease that converts hepatocyte growth factor to the active form. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],
Function：caution:It is uncertain whether Met-1 is the initiator.,function:Activates hepatocyte growth factor (HGF) by converting it from a single chain to a heterodimeric form.,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 fibronectin type-I domain.,similarity:Contains 1 fibronectin type-II domain.,similarity:Contains 1 kringle domain.,similarity:Contains 1 peptidase S1 domain.,similarity:Contains 2 EGF-like domains.,subcellular location:Secreted as an inactive single-chain precursor and is then activated to a heterodimeric form.,subunit:Heterodimer of a short chain and a long chain linked by a disulfide bond.,tissue specificity:Liver.,
Subcellular Location：Secreted. Secreted as an inactive single-chain precursor and is then activated to a heterodimeric form.
Expression：Liver.
