Target：SCAF1

Gene Name：SCAF1

Protein Name：Splicing factor arginine/serine-rich 19

Human Gene Id：58506

Human Swiss Prot No：Q9H7N4

Mouse Gene Id：233208

Mouse Swiss Prot No：Q5U4C3

Immunogen：The antiserum was produced against synthesized peptide derived from human SFRS19. AA range:41-90

Specificity：SCAF1 Polyclonal Antibody detects endogenous levels of SCAF1 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000;IHC 1:50-300

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：SCAF1;SFRS19;SRA1;Splicing factor; arginine/serine-rich 19;SR-related and CTD-associated factor 1;SR-related-CTD-associated factor;SCAF;Serine arginine-rich pre-mRNA splicing factor SR-A1;SR-A1

Observed Band(KD)：140kD

Background：function:May function in pre-mRNA splicing.,induction:Up-regulated by estrogens, androgens and glucocorticoids.,similarity:Belongs to the splicing factor SR family.,subunit:Interacts with POLR2A.,tissue specificity:Ubiquitous. Highly expressed in fetal brain and liver, poorly expressed in salivary gland, heart, skin and ovary. Expressed in colorectal carcinomas and ovarian cancers. Overexpressed in colorectal carcinomas as compared to normal colonic mucosa.,

Function：function:May function in pre-mRNA splicing.,induction:Up-regulated by estrogens, androgens and glucocorticoids.,similarity:Belongs to the splicing factor SR family.,subunit:Interacts with POLR2A.,tissue specificity:Ubiquitous. Highly expressed in fetal brain and liver, poorly expressed in salivary gland, heart, skin and ovary. Expressed in colorectal carcinomas and ovarian cancers. Overexpressed in colorectal carcinomas as compared to normal colonic mucosa.,

Subcellular Location：Nucleus .

Expression：Ubiquitous. Highly expressed in fetal brain and liver, poorly expressed in salivary gland, heart, skin and ovary. Expressed in colorectal carcinomas and ovarian cancers. Overexpressed in colorectal carcinomas as compared to normal colonic mucosa.