Target:SC65
Gene Name:LEPREL4 NOL55 SC65
Protein Name:Synaptonemal complex protein SC65 (Leprecan-like protein 4) (Nucleolar autoantigen No55)
Human Gene Id:10609
Human Swiss Prot No:Q92791
Mouse Swiss Prot No:Q8K2B0
Rat Swiss Prot No:Q64375
Immunogen:Synthesized peptide derived from human protein . at AA range: 380-460
Specificity:SC65 Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):48kD
Background: This nucleolar protein was first characterized because it was an autoantigen in cases on interstitial cystitis. The protein, with a predicted molecular weight of 50 kDa, appears to be localized in the particulate compartment of the interphase nucleolus, with a distribution distinct from that of nucleolar protein B23. During mitosis it is associated with chromosomes. [provided by RefSeq, Jul 2008],
Function:similarity:Belongs to the CRTAP/No55 family.,subcellular location:Localized uniformly throughout the granular component of the nucleolus and on the surface of chromosomes during mitosis.,
Subcellular Location:Endoplasmic reticulum .
Expression:Detected in fibroblasts (at protein level) (PubMed:23959653). Detected in spleen, prostate, testis, ovary, colon, pancreas, kidney, placenta and heart (PubMed:10952778).