Target：ACSA

Fields：Glycolysis / Gluconeogenesis;Pyruvate metabolism;Glyoxylate and dicarboxylate metabolism;Propanoate metabolism;Metabolic pathways;Carbon metabolism

Gene Name：ACSS2 ACAS2

Protein Name：Acetyl-coenzyme A synthetase, cytoplasmic (EC 6.2.1.1) (Acetate--CoA ligase) (Acetyl-CoA synthetase) (ACS) (AceCS) (Acyl-CoA synthetase short-chain family member 2) (Acyl-activating enzyme)

Human Gene Id：55902

Human Swiss Prot No：Q9NR19

Mouse Swiss Prot No：Q9QXG4

Immunogen：Synthesized peptide derived from human protein . at AA range: 40-120

Specificity：ACSA Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：77kD

Background： This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009],

Function：catalytic activity:ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA.,function:Activates acetate so that it can be used for lipid synthesis or for energy generation.,similarity:Belongs to the ATP-dependent AMP-binding enzyme family.,subunit:Monomer.,

Subcellular Location：Cytoplasm, cytosol .

Expression： Blood,Melanoma,Muscle,Platelet,Skin,Tongue,