Target:AKR1CL2
Gene Name:AKR1E2
Protein Name:1,5-anhydro-D-fructose reductase
Human Gene Id:83592
Human Swiss Prot No:Q96JD6
Mouse Swiss Prot No:Q9DCT1
Immunogen:The antiserum was produced against synthesized peptide derived from human AKR1CL2. AA range:141-190
Specificity:AKR1CL2 Polyclonal Antibody detects endogenous levels of AKR1CL2 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:AKR1E2;AKR1CL2;AKRDC1;1;5-anhydro-D-fructose reductase;AF reductase;Aldo-keto reductase family 1 member C-like protein 2;Aldo-keto reductase family 1 member E2;LoopADR;Testis-specific protein;hTSP
Observed Band(KD):37kD
Background: The protein encoded by this gene is a member of the aldo-keto reductase superfamily. Members in this family are characterized by their structure (evolutionarily highly conserved TIM barrel) and function (NAD(P)H-dependent oxido-reduction of carbonyl groups). Transcripts of this gene have been reported in specimens of human testis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012],
Function:catalytic activity:1,5-anhydro-D-glucitol + NADP(+) = 1,5-anhydro-D-fructose + NADPH.,function:Catalyzes the NADPH-dependent reduction of 1,5-anhydro-D-fructose (AF) to 1,5-anhydro-D-glucitol. Can also catalyze the reduction of various aldehydes and quinones.,similarity:Belongs to the aldo/keto reductase family.,tissue specificity:Testis-specific.,
Subcellular Location:Cytoplasm .
Expression:Specifically expressed in testis (PubMed:12604216, PubMed:15118078). Expressed in testicular germ cells and testis interstitial cells (PubMed:15118078).