Target：GRIP2

Gene Name：GRIP2 KIAA1719

Protein Name：Glutamate receptor-interacting protein 2 (GRIP-2)

Human Gene Id：80852

Human Swiss Prot No：Q9C0E4

Rat Swiss Prot No：Q9WTW1

Immunogen：Synthesized peptide derived from human protein . at AA range: 780-860

Specificity：GRIP2 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：114kD

Background：domain:PDZ 5 mediates the C-terminal binding of GRIA2 and GRIA3. PDZ 6 mediates interaction with the PDZ recognition motif of EFNB1. PDZ 7 mediates interaction with CSPG4.,function:May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons.,similarity:Belongs to the GRIP2 family.,similarity:Contains 7 PDZ (DHR) domains.,subunit:Interacts with EFNB1, EFNB3, GRIA2, GRIA3, CSPG4 and GRIPAP1. Can form homomultimers and heteromultimers with GRIP1 (By similarity). Interacts with the C-terminal tail of PRLHR.,

Function：domain:PDZ 5 mediates the C-terminal binding of GRIA2 and GRIA3. PDZ 6 mediates interaction with the PDZ recognition motif of EFNB1. PDZ 7 mediates interaction with CSPG4.,function:May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons.,similarity:Belongs to the GRIP2 family.,similarity:Contains 7 PDZ (DHR) domains.,subunit:Interacts with EFNB1, EFNB3, GRIA2, GRIA3, CSPG4 and GRIPAP1. Can form homomultimers and heteromultimers with GRIP1 (By similarity). Interacts with the C-terminal tail of PRLHR.,

Subcellular Location：Cytoplasm . Membrane ; Peripheral membrane protein .

Expression： Brain,Spleen,