Target:LDHC
Fields:Glycolysis / Gluconeogenesis;Cysteine and methionine metabolism;Pyruvate metabolism;Propanoate metabolism;Metabolic pathways;HIF-1 signaling pathway;Glucagon signaling pathway;Central carbon metabolism in cancer
Gene Name:LDHC LDH3 LDHX
Protein Name:L-lactate dehydrogenase C chain (LDH-C) (EC 1.1.1.27) (Cancer/testis antigen 32) (CT32) (LDH testis subunit) (LDH-X)
Human Gene Id:3948
Human Swiss Prot No:P07864
Mouse Swiss Prot No:P00342
Rat Swiss Prot No:P19629
Immunogen:Synthesized peptide derived from human protein . at AA range: 170-250
Specificity:LDHC Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):36kD
Background: Lactate dehydrogenase C catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. LDHC is testis-specific and belongs to the lactate dehydrogenase family. Two transcript variants have been detected which differ in the 5' untranslated region. [provided by RefSeq, Jul 2008],
Function:catalytic activity:(S)-lactate + NAD(+) = pyruvate + NADH.,function:Possible role in sperm motility.,online information:Lactate dehydrogenase entry,pathway:Fermentation; pyruvate fermentation to lactate; (S)-lactate from pyruvate: step 1/1.,similarity:Belongs to the LDH/MDH superfamily. LDH family.,subunit:Homotetramer.,
Subcellular Location:Cytoplasm.
Expression: Brain,Testis,