Target：RRAGD

Fields：Autophagy - animal;mTOR signaling pathway;Shigellosis

Gene Name：RRAGD

Protein Name：Ras-related GTP-binding protein D (Rag D) (RagD)

Human Gene Id：58528

Human Swiss Prot No：Q9NQL2

Mouse Swiss Prot No：Q7TT45

Immunogen：Synthesized peptide derived from human protein . at AA range: 140-220

Specificity：RRAGD Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：IP 1:50-200 WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：44kD

Background： RRAGD is a monomeric guanine nucleotide-binding protein, or G protein. By binding GTP or GDP, small G proteins act as molecular switches in numerous cell processes and signaling pathways.[supplied by OMIM, Apr 2004],

Function：function:Has guanine nucleotide-binding activity but lacks intrinsic GTPase activity.,similarity:Belongs to the GTR/RAG GTP-binding protein family.,subcellular location:Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state of associated RRAGA.,subunit:Forms a heterodimer with RRAGA in a sequence-independent manner. Binds GTP. Interacts with NOL8 and RRAGB.,

Subcellular Location：Cytoplasm . Nucleus . Lysosome . Predominantly cytoplasmic. May shuttle between the cytoplasm and nucleus, depending on the bound nucleotide state of associated RRAGA (PubMed:11073942). .

Expression： Amygdala,Lung,