Target：LGR6

Fields：Wnt signaling pathway

Gene Name：LGR6

Protein Name：Leucine-rich repeat-containing G-protein coupled receptor 6

Human Gene Id：59352

Human Swiss Prot No：Q9HBX8

Mouse Swiss Prot No：Q3UVD5

Immunogen：The antiserum was produced against synthesized peptide derived from human LGR6. AA range:471-520

Specificity：LGR6 Polyclonal Antibody detects endogenous levels of LGR6 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000;IHC 1:50-300

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：LGR6;Leucine-rich repeat-containing G-protein coupled receptor 6

Observed Band(KD)：104kD

Background： This gene encodes a member of the leucine-rich repeat-containing subgroup of the G protein-coupled 7-transmembrane protein superfamily. The encoded protein is a glycoprotein hormone receptor with a large N-terminal extracellular domain that contains leucine-rich repeats important for the formation of a horseshoe-shaped interaction motif for ligand binding. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008],

Function：function:Orphan receptor.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the G-protein coupled receptor 1 family.,similarity:Contains 16 LRR (leucine-rich) repeats.,

Subcellular Location：Cell membrane ; Multi-pass membrane protein .

Expression： Mammary gland,