Target：LHX4

Gene Name：LHX4

Protein Name：LIM/homeobox protein Lhx4 (LIM homeobox protein 4)

Human Gene Id：89884

Human Swiss Prot No：Q969G2

Mouse Swiss Prot No：P53776

Immunogen：Synthesized peptide derived from human protein . at AA range: 160-240

Specificity：LHX4 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：42kD

Background： This gene encodes a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor involved in the control of differentiation and development of the pituitary gland. Mutations in this gene cause combined pituitary hormone deficiency 4. [provided by RefSeq, Dec 2010],

Function：disease:A chromosomal aberration involving LHX4 may be a cause of acute lymphoblastic leukemia. Translocation t(1;14)(q25;q32) with IGHG1.,disease:Defects in LHX4 are the cause of Machinis syndrome [MIM:606606]. It is characterized by short stature, pituitary and cerebellar defects, and small sella turcica.,function:May play a critical role in the development of respiratory control mechanisms and in the normal growth and maturation of the lung.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 LIM zinc-binding domain.,similarity:Contains 2 LIM zinc-binding domains.,

Subcellular Location：Nucleus .

Expression： Muscle,Placenta,