Target：LHX5

Fields：Signaling pathways regulating pluripotency of stem cells

Gene Name：LHX5

Protein Name：LIM/homeobox protein Lhx5 (LIM homeobox protein 5)

Human Gene Id：64211

Human Swiss Prot No：Q9H2C1

Mouse Swiss Prot No：P61375

Rat Swiss Prot No：P61376

Immunogen：Synthesized peptide derived from human protein . at AA range: 130-210

Specificity：LHX5 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：44kD

Background： This gene encodes a protein belonging to a large protein family, members of which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator and be involved in the control of differentiation and development of the forebrain. In mice, this protein is essential for the regulation of precursor cell proliferation and the control of neuronal differentiation and migration during hippocampal development. This protein is involved in learning and motor functions in adult mice. [provided by RefSeq, Jul 2008],

Function：function:Plays an essential role in the regulation of neuronal differentiation and migration during development of the central nervous system.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 2 LIM zinc-binding domains.,tissue specificity:Expressed in fetal brain and in various regions of the adult central nervous system including the spinal cord, the thalamus, and the cerebellum.,

Subcellular Location：Nucleus .

Expression：Expressed in fetal brain and in various regions of the adult central nervous system including the spinal cord, the thalamus, and the cerebellum.