Target：LIR-6

Fields：Osteoclast differentiation;B cell receptor signaling pathway

Gene Name：LILRA1

Protein Name：Leukocyte immunoglobulin-like receptor subfamily A member 1

Human Gene Id：11024

Human Swiss Prot No：O75019

Immunogen：The antiserum was produced against synthesized peptide derived from human LILRA1. AA range:53-102

Specificity：LIR-6 Polyclonal Antibody detects endogenous levels of LIR-6 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000;IHC 1:50-300

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：LILRA1;LIR6;Leukocyte immunoglobulin-like receptor subfamily A member 1;CD85 antigen-like family member I;Leukocyte immunoglobulin-like receptor 6;LIR-6;CD antigen CD85i

Observed Band(KD)：53kD

Background： This gene encodes an activating member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein is predominantly expressed in B cells, interacts with major histocompatibility complex class I ligands, and contributes to the regulation of immune responses. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013],

Function：function:May act as receptor for class I MHC antigens.,similarity:Contains 4 Ig-like C2-type (immunoglobulin-like) domains.,tissue specificity:Detected in monocytes and B-cells.,

Subcellular Location：Membrane; Single-pass type I membrane protein.

Expression：Detected in monocytes and B-cells.