Target：LMTK1
Gene Name：AATK AATYK KIAA0641 LMR1 LMTK1
Protein Name：Serine/threonine-protein kinase LMTK1 (EC 2.7.11.1) (Apoptosis-associated tyrosine kinase) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (Lemur tyrosine kinase 1) (p35-bi
Human Gene Id：9625
Human Swiss Prot No：Q6ZMQ8
Mouse Swiss Prot No：Q80YE4
Immunogen：Synthesized peptide derived from human protein . at AA range: 1110-1190
Specificity：LMTK1 Polyclonal Antibody detects endogenous levels of protein.
Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500-2000 ELISA 1:5000-20000
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD)：151kD
Background： The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011],
Function：catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:May be involved in neuronal differentiation.,induction:Up-regulated during apoptosis.,PTM:Autophosphorylated. Phosphorylated by CDK5.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity:Contains 1 protein kinase domain.,subcellular location:Predominantly perinuclear.,subunit:Interacts with CDK5.,tissue specificity:Expressed in brain.,
Subcellular Location：Membrane ; Single-pass type I membrane protein . Cytoplasm . Cytoplasm, perinuclear region . Predominantly perinuclear.
Expression：Expressed in brain.
