Target:CDNF
Gene Name:CDNF ARMETL1
Protein Name:Cerebral dopamine neurotrophic factor (ARMET-like protein 1) (Conserved dopamine neurotrophic factor)
Human Gene Id:441549
Human Swiss Prot No:Q49AH0
Mouse Gene Id:227526
Mouse Swiss Prot No:Q8CC36
Immunogen:Synthetic peptide from human protein at AA range: 31-80
Specificity:The antibody detects endogenous CDNF
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:IHC 1:50-200, ELISA 1:10000-20000. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:Cerebral dopamine neurotrophic factor (ARMET-like protein 1;Conserved dopamine neurotrophic factor)
Background:CDNF (Cerebral Dopamine Neurotrophic Factor) is a Protein Coding gene. Trophic factor for dopamine neurons. Prevents the 6-hydroxydopamine (6-OHDA)-induced degeneration of dopaminergic neurons. When administered after 6-OHDA-lesioning, restores the dopaminergic function and prevents the degeneration of dopaminergic neurons in substantia nigra (By similarity).
Subcellular Location:Secreted .
Expression:Widely expressed in neuronal and non-neuronal tissues. In the brain, highest levels in the optic nerve and corpus callosum.