Target:CDK3
Gene Name:CDK3 CDKN3
Protein Name:Cyclin-dependent kinase 3 (EC 2.7.11.22) (Cell division protein kinase 3)
Human Gene Id:1018
Human Swiss Prot No:Q00526
Mouse Swiss Prot No:Q80YP0
Immunogen:Synthesized peptide derived from human protein . at AA range: 10-90
Specificity:CDK3 Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):33kD
Background:cyclin dependent kinase 3(CDK3) Homo sapiens This gene encodes a member of the cyclin-dependent protein kinase family. The protein promotes entry into S phase, in part by activating members of the E2F family of transcription factors. The protein also associates with cyclin C and phosphorylates the retinoblastoma 1 protein to promote exit from G0. [provided by RefSeq, Jul 2008],
Function:catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Probably involved in the control of the cell cycle. Interacts with a yet unknown type of cyclin. Can phosphorylate histone H1.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with CABLES1.,
Expression:Expressed in cancer cell lines and glioblastoma tissue.