Target：GNRH1
Fields：Neuroactive ligand-receptor interaction;GnRH signaling pathway;GnRH secretion
Gene Name：GNRH1
Protein Name：Progonadoliberin-1
Human Gene Id：2796
Human Swiss Prot No：P01148
Mouse Swiss Prot No：P13562
Immunogen：The antiserum was produced against synthesized peptide derived from human GnRH I. AA range:43-92
Specificity：GnRH I Polyclonal Antibody detects endogenous levels of GnRH I protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：GNRH1;GNRH;GRH;LHRH;Progonadoliberin-1;Progonadoliberin I
Molecular Weight(Da)：10kD
Background：gonadotropin releasing hormone 1(GNRH1) Homo sapiens This gene encodes a preproprotein that is proteolytically processed to generate a peptide that is a member of the gonadotropin-releasing hormone (GnRH) family of peptides. Alternative splicing results in multiple transcript variants, at least one of which is secreted and then cleaved to generate gonadoliberin-1 and GnRH-associated peptide 1. Gonadoliberin-1 stimulates the release of luteinizing and follicle stimulating hormones, which are important for reproduction. Mutations in this gene are associated with hypogonadotropic hypogonadism. [provided by RefSeq, Nov 2015],
Function：function:Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones.,online information:Gonadotropin-releasing hormone entry,pharmaceutical:Available under the names Factrel (Ayerst Labs), Lutrepulse or Lutrelef (Ferring Pharmaceuticals) and Relisorm (Serono). Used in evaluating hypothalamic-pituitary gonadotropic function.,similarity:Belongs to the GnRH family.,
Subcellular Location：Secreted.
Expression： Brain,
