Target：GNL1

Gene Name：GNL1

Protein Name：Guanine nucleotide-binding protein-like 1

Human Gene Id：2794

Human Swiss Prot No：P36915

Mouse Gene Id：14670

Mouse Swiss Prot No：P36916

Rat Gene Id：309593

Rat Swiss Prot No：Q6MG06

Immunogen：The antiserum was produced against synthesized peptide derived from human GNL1. AA range:61-110

Specificity：GNL1 Polyclonal Antibody detects endogenous levels of GNL1 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：GNL1;HSR1;Guanine nucleotide-binding protein-like 1;GTP-binding protein HSR1

Observed Band(KD)：69kD

Background： The GNL1 gene, identified in the human major histocompatibility complex class I region, shows a high degree of similarity with its mouse counterpart. The GNL1 gene is located less than 2 kb centromeric to HLA-E, in the same transcriptional orientation. GNL1 is telomeric to HLA-B and HLA-C. [provided by RefSeq, Jul 2008],

Function：domain:In contrast to other GTP-binding proteins, this family is characterized by a circular permutation of the GTPase motifs described by a G4-G1-G3 pattern.,function:Possible regulatory or functional link with the histocompatibility cluster.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the MMR1/HSR1 GTP-binding protein family.,

Subcellular Location：extracellular space,nucleus,

Expression： Cervix,Muscle,Peripheral blood leukocyte,Skin,T-cell,