Target:Maspin
Fields:p53 signaling pathway;MicroRNAs in cancer
Gene Name:SERPINB5
Protein Name:Serpin B5
Human Gene Id:5268
Human Swiss Prot No:P36952
Mouse Gene Id:20724
Mouse Swiss Prot No:P70124
Rat Gene Id:116589
Rat Swiss Prot No:P70564
Immunogen:The antiserum was produced against synthesized peptide derived from human Serpin B5. AA range:91-140
Specificity:Maspin Polyclonal Antibody detects endogenous levels of Maspin protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:SERPINB5;PI5;Serpin B5;Maspin;Peptidase inhibitor 5;PI-5
Observed Band(KD):40kD
Background:function:Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.,similarity:Belongs to the serpin family. Ov-serpin subfamily.,tissue specificity:Normal mammary epithelial cells.,
Function:function:Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.,similarity:Belongs to the serpin family. Ov-serpin subfamily.,tissue specificity:Normal mammary epithelial cells.,
Subcellular Location:Secreted, extracellular space.
Expression:Normal mammary epithelial cells.