Target：BRD3

Gene Name：BRD3

Protein Name：Bromodomain-containing protein 3

Human Gene Id：8019

Human Swiss Prot No：Q15059

Mouse Gene Id：67382

Mouse Swiss Prot No：Q8K2F0

Immunogen：The antiserum was produced against synthesized peptide derived from human BRD3. AA range:611-660

Specificity：BRD3 Polyclonal Antibody detects endogenous levels of BRD3 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：BRD3;KIAA0043;RING3L;Bromodomain-containing protein 3;RING3-like protein

Observed Band(KD)：90kD

Background： This gene was identified based on its homology to the gene encoding the RING3 protein, a serine/threonine kinase. The gene localizes to 9q34, a region which contains several major histocompatibility complex (MHC) genes. The function of the encoded protein is not known. [provided by RefSeq, Jul 2008],

Function：disease:A chromosomal aberration involving BRD3 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;9)(q14;q34) with NUT which produces a BRD3-NUT fusion protein.,similarity:Contains 2 bromo domains.,tissue specificity:Ubiquitous.,

Subcellular Location：Nucleus . Detected on chromatin. .

Expression：Ubiquitous.