Target:BORG5
Gene Name:CDC42EP1 BORG5 CEP1 MSE55
Protein Name:Cdc42 effector protein 1 (Binder of Rho GTPases 5) (Serum protein MSE55)
Human Gene Id:11135
Human Swiss Prot No:Q00587
Mouse Swiss Prot No:Q91W92
Rat Swiss Prot No:A1A5P0
Immunogen:Synthesized peptide derived from part region of human protein
Specificity:BORG5 Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):43kD
Background: CDC42 is a member of the Rho GTPase family that regulates multiple cellular activities, including actin polymerization. The protein encoded by this gene is a CDC42 binding protein that mediates actin cytoskeleton reorganization at the plasma membrane. This protein is secreted and is primarily found in bone marrow. [provided by RefSeq, Jul 2008],
Function:domain:The CRIB domain mediates interaction with CDC42.,function:Probably involved in the organization of the actin cytoskeleton. Induced membrane extensions in fibroblasts.,similarity:Belongs to the BORG/CEP family.,similarity:Contains 1 CRIB domain.,subunit:Interacts with RHOQ and CDC42, in a GTP-dependent manner.,tissue specificity:Endothelial and bone marrow stromal cells.,
Subcellular Location:Endomembrane system ; Peripheral membrane protein . Cytoplasm, cytoskeleton .
Expression:Endothelial and bone marrow stromal cells.