Target：ARHGAP1

Gene Name：ARHGAP1

Protein Name：Rho GTPase-activating protein 1

Human Gene Id：392

Human Swiss Prot No：Q07960

Mouse Gene Id：228359

Mouse Swiss Prot No：Q5FWK3

Immunogen：The antiserum was produced against synthesized peptide derived from human RHG1. AA range:189-238

Specificity：ARHGAP1 Polyclonal Antibody detects endogenous levels of ARHGAP1 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：ARHGAP1;CDC42GAP;RHOGAP1;Rho GTPase-activating protein 1;CDC42 GTPase-activating protein;GTPase-activating protein rhoOGAP;Rho-related small GTPase protein activator;Rho-type GTPase-activating protein 1;p50-RhoGAP

Observed Band(KD)：50kD

Background： This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein contains a SRC homology 3 domain and interacts with Bcl-2-associated protein family members. [provided by RefSeq, Aug 2012],

Function：function:GTPase activator for the Rho, Rac and Cdc42 proteins, converting them to the putatively inactive GDP-bound state. Cdc42 seems to be the preferred substrate.,similarity:Contains 1 CRAL-TRIO domain.,similarity:Contains 1 Rho-GAP domain.,subunit:Found in a complex with XPO7, EIF4A1, ARHGAP1, VPS26A, VPS29, VPS35 and SFN. Interacts with BNIPL.,tissue specificity:Ubiquitous.,

Subcellular Location：Cytoplasm.

Expression：Ubiquitous.