Target：Dvl-3
Fields：mTOR signaling pathway;Wnt signaling pathway;Notch signaling pathway;Hippo signaling pathway;Signaling pathways regulating pluripotency of stem cells;Melanogenesis;Cushing syndrome;Alzheimer disease;Pathways of neurodegeneration - multiple diseases;Human papillomavirus infection;Pathways in cancer;Basal cell carcinoma;Breast cancer;Hepatocellular carcinoma;Gastric cancer
Gene Name：DVL3
Protein Name：Segment polarity protein dishevelled homolog DVL-3
Human Gene Id：1857
Human Swiss Prot No：Q92997
Mouse Gene Id：13544
Mouse Swiss Prot No：Q61062
Immunogen：The antiserum was produced against synthesized peptide derived from human DVL3. AA range:326-375
Specificity：Dvl-3 Polyclonal Antibody detects endogenous levels of Dvl-3 protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：DVL3;KIAA0208;Segment polarity protein dishevelled homolog DVL-3;Dishevelled-3;DSH homolog 3
Molecular Weight(Da)：78kD
Background： This gene is a member of a multi-gene family which shares strong similarity with the Drosophila dishevelled gene, dsh. The Drosophila dishevelled gene encodes a cytoplasmic phosphoprotein that regulates cell proliferation. [provided by RefSeq, Jul 2008],
Function：function:May play a role in the signal transduction pathway mediated by multiple Wnt genes.,similarity:Belongs to the DSH family.,similarity:Contains 1 DEP domain.,similarity:Contains 1 DIX domain.,similarity:Contains 1 PDZ (DHR) domain.,subunit:Interacts (via the PDZ domain) with the C-terminal regions of VANGL1 and VANGL2 (By similarity). Interacts (via the region containing both the PDZ and DEP domains) with LRRFIP2; the DIX domain may inhibit this interaction.,
Subcellular Location：Cytoplasm .
Expression： Bone marrow,Brain,Hippocampus,Placenta,Uterus,
