Target：DUSP19

Gene Name：DUSP19

Protein Name：Dual specificity protein phosphatase 19

Human Gene Id：142679

Human Swiss Prot No：Q8WTR2

Mouse Swiss Prot No：Q8K4T5

Immunogen：The antiserum was produced against synthesized peptide derived from human DUSP19. AA range:111-160

Specificity：DUSP19 Polyclonal Antibody detects endogenous levels of DUSP19 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：DUSP19;DUSP17;LMWDSP3;SKRP1;Dual specificity protein phosphatase 19;Dual specificity phosphatase TS-DSP1;Low molecular weight dual specificity phosphatase 3;LMW-DSP3;Protein phosphatase SKRP1;Stress-activated protein kinase pathway

Observed Band(KD)：28kD

Background：dual specificity phosphatase 19(DUSP19) Homo sapiens Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP19 contains a variation of the consensus DUSP C-terminal catalytic domain, with the last serine residue replaced by alanine, and lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009 [PubMed 19228121]).[supplied by OMIM, Dec 2009],

Function：catalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,function:Has a dual specificity toward Ser/Thr and Tyr-containing proteins.,similarity:Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.,similarity:Contains 1 tyrosine-protein phosphatase domain.,tissue specificity:Expressed in the heart, lung, liver, and pancreas. The expression level in the pancreas is the highest.,

Expression：Expressed in the heart, lung, liver, and pancreas. The expression level in the pancreas is the highest.