Target：Dmc1

Gene Name：DMC1

Protein Name：Meiotic recombination protein DMC1/LIM15 homolog

Human Gene Id：11144

Human Swiss Prot No：Q14565

Mouse Gene Id：13404

Mouse Swiss Prot No：Q61880

Immunogen：The antiserum was produced against synthesized peptide derived from human DMC1. AA range:61-110

Specificity：Dmc1 Polyclonal Antibody detects endogenous levels of Dmc1 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：DMC1;DMC1H;LIM15;Meiotic recombination protein DMC1/LIM15 homolog

Molecular Weight(Da)：38kD

Background：DNA meiotic recombinase 1(DMC1) Homo sapiens This gene encodes a member of the superfamily of recombinases (also called DNA strand-exchange proteins). Recombinases are important for repairing double-strand DNA breaks during mitosis and meiosis. This protein, which is evolutionarily conserved, is reported to be essential for meiotic homologous recombination and may thus play an important role in generating diversity of genetic information. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013],

Function：function:May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks.,similarity:Belongs to the recA family. DMC1 subfamily.,similarity:Contains 1 HhH domain.,subunit:Interacts with the MND1-PSMC3IP heterodimer (By similarity). Double stacked ring-shaped homooctamer.,

Subcellular Location：Nucleus . Chromosome .

Expression： Ovary,Testis,Thymus,