Target:DHHC-9
Gene Name:ZDHHC9
Protein Name:Palmitoyltransferase ZDHHC9
Human Gene Id:51114
Human Swiss Prot No:Q9Y397
Mouse Gene Id:208884
Mouse Swiss Prot No:P59268
Immunogen:The antiserum was produced against synthesized peptide derived from human ZDHHC9. AA range:315-364
Specificity:DHHC-9 Polyclonal Antibody detects endogenous levels of DHHC-9 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:ZDHHC9;CXorf11;ZDHHC10;ZNF379;ZNF380;CGI-89;Palmitoyltransferase ZDHHC9;Zinc finger DHHC domain-containing protein 9;DHHC-9;DHHC9;Zinc finger protein 379;Zinc finger protein 380
Observed Band(KD):41kD
Background: This gene encodes an integral membrane protein that is a member of the zinc finger DHHC domain-containing protein family. The encoded protein forms a complex with golgin subfamily A member 7 and functions as a palmitoyltransferase. This protein specifically palmitoylates HRAS and NRAS. Mutations in this gene are associated with X-linked mental retardation. Alternate splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq, May 2010],
Function:catalytic activity:Palmitoyl-CoA + protein-cysteine = S-palmitoyl protein + CoA.,domain:The DHHC domain is required for palmitoyltransferase activity.,function:The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS.,similarity:Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.,similarity:Contains 1 DHHC-type zinc finger.,subunit:Interacts with GOLGA7.,tissue specificity:Highly expressed in kidney, skeletal muscle, brain, lung and liver. Absent in thymus, spleen and leukocytes.,
Subcellular Location:Endoplasmic reticulum membrane ; Multi-pass membrane protein . Golgi apparatus membrane ; Multi-pass membrane protein .
Expression:Highly expressed in kidney, skeletal muscle, brain, lung and liver. Absent in thymus, spleen and leukocytes.