Target：DHB14

Gene Name：HSD17B14 DHRS10 SDR3 UNQ502/PRO474

Protein Name：17-beta-hydroxysteroid dehydrogenase 14 (17-beta-HSD 14) (EC 1.1.1.-) (17-beta-hydroxysteroid dehydrogenase DHRS10) (Dehydrogenase/reductase SDR family member 10) (Retinal short-chain dehydrogenase/re

Human Gene Id：51171

Human Swiss Prot No：Q9BPX1

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：DHB14 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：29kD

Background： 17-beta-hydroxysteroid dehydrogenases, such as HSD17B14, are primarily involved in metabolism of steroids at the C17 position and also of other substrates, such as fatty acids, prostaglandins, and xenobiotics (Lukacik et al., 2007 [PubMed 17067289]).[supplied by OMIM, Jun 2009],

Function：function:Has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone. The physiological substrate is not known. Acts on oestradiol and 5-androstene-3-beta,17-beta-diol (in vitro).,similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family.,subunit:Homotetramer.,tissue specificity:Highly expressed in brain, placenta, liver and kidney.,

Subcellular Location：Cytoplasm .

Expression：Highly expressed in brain, placenta, liver and kidney.