Target：GATA-6

Gene Name：GATA6

Protein Name：Transcription factor GATA-6

Human Gene Id：2627

Human Swiss Prot No：Q92908

Mouse Gene Id：14465

Mouse Swiss Prot No：Q61169

Rat Gene Id：29300

Rat Swiss Prot No：P46153

Immunogen：The antiserum was produced against synthesized peptide derived from human GATA6. AA range:461-510

Specificity：GATA-6 Polyclonal Antibody detects endogenous levels of GATA-6 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：GATA6;Transcription factor GATA-6;GATA-binding factor 6

Observed Band(KD)：45kD

Background： This gene is a member of a small family of zinc finger transcription factors that play an important role in the regulation of cellular differentiation and organogenesis during vertebrate development. This gene is expressed during early embryogenesis and localizes to endo- and mesodermally derived cells during later embryogenesis and thereby plays an important role in gut, lung, and heart development. Mutations in this gene are associated with several congenital defects. [provided by RefSeq, Mar 2012],

Function：function:Thought to be important for regulating terminal differentiation and/or proliferation.,similarity:Contains 2 GATA-type zinc fingers.,tissue specificity:Expressed in heart, gut and gut-derived tissues.,

Subcellular Location：Nucleus .

Expression：Expressed in heart, gut and gut-derived tissues. Expressed in skin upper pilosebaceous unit. Expression is decreased or lost in acne lesions (PubMed:33082341).