Target：Connexin 31.3

Gene Name：GJC3

Protein Name：Gap junction gamma-3 protein

Human Gene Id：349149

Human Swiss Prot No：Q8NFK1

Mouse Swiss Prot No：Q921C1

Immunogen：The antiserum was produced against synthesized peptide derived from human GJC3. AA range:151-200

Specificity：Connexin 31.3 Polyclonal Antibody detects endogenous levels of Connexin 31.3 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：GJC3;GJE1;Gap junction gamma-3 protein;Connexin-30.2;Cx30.2;Connexin-31.3;Cx31.3;Gap junction epsilon-1 protein

Observed Band(KD)：28kD

Background： This gene encodes a gap junction protein. The encoded protein, also known as a connexin, plays a role in formation of gap junctions, which provide direct connections between neighboring cells. Mutations in this gene have been reported to be associated with nonsyndromic hearing loss.[provided by RefSeq, Feb 2010],

Function：function:One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.,similarity:Belongs to the connexin family. Gamma-type subfamily.,subunit:A connexon is composed of a hexamer of connexins.,tissue specificity:CNS specific. Expression is restricted to brain, spinal cord, and sciatic nerve. According to PubMed:12881038 expression is abundant in skeletal muscle, liver, and heart, and to a minor degree in pancreas and kidney.,

Subcellular Location：Cell membrane ; Multi-pass membrane protein . Cell junction, gap junction .

Expression：CNS specific. Expression is restricted to brain, spinal cord, and sciatic nerve. According to PubMed:12881038, expression is abundant in skeletal muscle, liver, and heart, and to a minor degree in pancreas and kidney.