Target:InsP6 Kinase 3
Fields:Phosphatidylinositol signaling system
Gene Name:IP6K3
Protein Name:Inositol hexakisphosphate kinase 3
Human Gene Id:117283
Human Swiss Prot No:Q96PC2
Mouse Gene Id:271424
Mouse Swiss Prot No:Q8BWD2
Immunogen:The antiserum was produced against synthesized peptide derived from human IP6K3. AA range:201-250
Specificity:InsP6 Kinase 3 Polyclonal Antibody detects endogenous levels of InsP6 Kinase 3 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:IP6K3;IHPK3;Inositol hexakisphosphate kinase 3;InsP6 kinase 3;Inositol hexaphosphate kinase 3
Observed Band(KD):51kD
Background: This gene encodes a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Dec 2008],
Function:catalytic activity:ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate = ADP + diphospho-1D-myo-inositol tetrakisphosphate (isomeric configuration unknown).,catalytic activity:ATP + 1D-myo-inositol hexakisphosphate = ADP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate.,function:Converts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4.,similarity:Belongs to the inositol phosphokinase (IPK) family.,tissue specificity:Detected in brain.,
Subcellular Location:Cytoplasm .
Expression:Detected in brain.