Target：FGF-13

Gene Name：FGF13

Protein Name：Fibroblast growth factor 13

Human Gene Id：2258

Human Swiss Prot No：Q92913

Mouse Gene Id：14168

Mouse Swiss Prot No：P70377

Rat Gene Id：84488

Rat Swiss Prot No：Q9ERW3

Immunogen：The antiserum was produced against synthesized peptide derived from human FGF13. AA range:154-203

Specificity：FGF-13 Polyclonal Antibody detects endogenous levels of FGF-13 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：FGF13;FHF2;Fibroblast growth factor 13;FGF-13;Fibroblast growth factor homologous factor 2;FHF-2

Observed Band(KD)：28kD

Background： The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene is located in a region on chromosome X, which is associated with Borjeson-Forssman-Lehmann syndrome (BFLS), making it a possible candidate gene for familial cases of the BFLS, and for other syndromal and nonspecific forms of X-linked mental retardation mapping to this region. Alternative splicing of this gene at the 5' end results in several transcript variants encoding different isoforms with different N-termini. [provided by RefSeq, Nov 2008],

Function：function:Probably involved in nervous system development and function.,similarity:Belongs to the heparin-binding growth factors family.,tissue specificity:Nervous system.,

Subcellular Location：[Isoform 1]: Nucleus .; [Isoform 2]: Cytoplasm . Nucleus .; [Isoform 3]: Cytoplasm . Nucleus .; [Isoform 4]: Cytoplasm . Nucleus .; [Isoform 5]: Cytoplasm . Nucleus .; Cell projection, filopodium . Cell projection, growth cone . Cell projection, dendrite . Cell membrane, sarcolemma . Cytoplasm . Not secreted. Localizes to the lateral membrane and intercalated disks of myocytes. .

Expression：Ubiquitously expressed. Predominantly expressed in the nervous system.