Target：NCoA-7
Fields：Lysosome
Gene Name：NCOA7
Protein Name：Nuclear receptor coactivator 7
Human Gene Id：135112
Human Swiss Prot No：Q8NI08
Mouse Swiss Prot No：Q6DFV7
Immunogen：The antiserum was produced against synthesized peptide derived from human NCOA7. AA range:422-471
Specificity：NCoA-7 Polyclonal Antibody detects endogenous levels of NCoA-7 protein.
Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source：Polyclonal, Rabbit,IgG
Dilution：WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration：1 mg/ml
Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name：NCOA7;ERAP140;ESNA1;Nbla00052;Nbla10993;Nuclear receptor coactivator 7;140 kDa estrogen receptor-associated protein;Estrogen nuclear receptor coactivator 1
Observed Band(KD)：106kD
Background：function:Enhances the transcriptional activities of several nuclear receptors. Involved in the coactivation of different nuclear receptors, such as ESR1, THRB, PPARG and RARA.,similarity:Belongs to the OXR1 family.,similarity:Contains 1 LysM repeat.,similarity:Contains 1 TLD domain.,subunit:Interacts with ESR1, ESR2A, ESR2B, THRB, PPARG and RARA in a ligand-inducible manner. Interacts with the heterodimer AHR-ARNT.,tissue specificity:Highly expressed in brain. Weakly expressed in mammary gland, ovary, uterus, prostate, stomach, bladder, spinal cord and pancreas. Expressed in cancer cell line.,
Function：function:Enhances the transcriptional activities of several nuclear receptors. Involved in the coactivation of different nuclear receptors, such as ESR1, THRB, PPARG and RARA.,similarity:Belongs to the OXR1 family.,similarity:Contains 1 LysM repeat.,similarity:Contains 1 TLD domain.,subunit:Interacts with ESR1, ESR2A, ESR2B, THRB, PPARG and RARA in a ligand-inducible manner. Interacts with the heterodimer AHR-ARNT.,tissue specificity:Highly expressed in brain. Weakly expressed in mammary gland, ovary, uterus, prostate, stomach, bladder, spinal cord and pancreas. Expressed in cancer cell line.,
Subcellular Location：Nucleus .
Expression：Highly expressed in brain. Weakly expressed in mammary gland, ovary, uterus, prostate, stomach, bladder, spinal cord and pancreas. Expressed in cancer cell line.
