Target:Myogenin
Gene Name:MYOG
Protein Name:Myogenin
Human Gene Id:4656
Human Swiss Prot No:P15173
Mouse Gene Id:17928
Mouse Swiss Prot No:P12979
Rat Gene Id:29148
Rat Swiss Prot No:P20428
Immunogen:The antiserum was produced against synthesized peptide derived from human Myogenin. AA range:50-99
Specificity:Myogenin Polyclonal Antibody detects endogenous levels of Myogenin protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:IHC: 100-300.WB 1:500 - 1:2000. ELISA: 1:10000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:MYOG;BHLHC3;MYF4;Myogenin;Class C basic helix-loop-helix protein 3;bHLHc3;Myogenic factor 4;Myf-4
Observed Band(KD):39kD
Background: Myogenin is a muscle-specific transcription factor that can induce myogenesis in a variety of cell types in tissue culture. It is a member of a large family of proteins related by sequence homology, the helix-loop-helix (HLH) proteins. It is essential for the development of functional skeletal muscle. [provided by RefSeq, Jul 2008],
Function:function:Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Efficient DNA binding requires dimerization with another bHLH protein.,
Subcellular Location:Nucleus. Recruited to late myogenic gene promoter regulatory sequences with SMARCA4/BRG1/BAF190A and SWI/SNF chromatin-remodeling enzymes to promote chromatin-remodeling and transcription initiation in developing embryos. .
Expression: Eye,Skeletal muscle,