Target：MUC3A

Gene Name：MUC3A MUC3

Protein Name：Mucin-3A (MUC-3A) (Intestinal mucin-3A)

Human Swiss Prot No：Q02505

Immunogen：Synthesized peptide derived from part region of human protein

Specificity：MUC3A Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：IHC 1:50-300. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：279kD

Background： The mucin genes encode epithelial glycoproteins, some of which are secreted and some membrane bound. Each of the genes contains at least one large domain of tandemly repeated sequence that encodes the peptide sequence rich in serine and/or threonine residues, which carries most of the O-linked glycosylation (Gendler and Spicer, 1995 [PubMed 7778880]).[supplied by OMIM, Aug 2008],

Function：alternative products:Additional isoforms seem to exist,function:Major glycoprotein component of a variety of mucus gels. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces.,function:Major glycoprotein component of a variety of mucus gels. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. May be involved in ligand binding and intracellular signaling.,PTM:Highly O-glycosylated and probably also N-glycosylated.,similarity:Contains 1 EGF-like domain.,similarity:Contains 1 SEA domain.,tissue specificity:Broad specificity; small intestine, colon, colonic tumors, heart, liver, thymus, prostate, pancreas and gall bladder.,tissue specificity:Fetal and adult small intestine and fetal and adult colon.,

Subcellular Location：[Isoform 1]: Membrane; Single-pass membrane protein .; [Isoform 2]: Secreted .; [Isoform 3]: Secreted .; [Isoform 4]: Secreted .; [Isoform 5]: Secreted.

Expression：Broad specificity; small intestine, colon, colonic tumors, heart, liver, thymus, prostate, pancreas and gall bladder.