Target：MPRB

Fields：Chemical carcinogenesis - receptor activation

Gene Name：PAQR8 C6orf33 LMPB1 MPRB

Protein Name：Membrane progestin receptor beta (mPR beta) (Lysosomal membrane protein in brain 1) (Progestin and adipoQ receptor family member 8) (Progestin and adipoQ receptor family member VIII)

Human Gene Id：85315

Human Swiss Prot No：Q8TEZ7

Mouse Swiss Prot No：Q80ZE5

Immunogen：Synthesized peptide derived from human protein . at AA range: 280-360

Specificity：MPRB Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：38kD

Background：function:Steroid membrane receptor. Binds progesterone. May be involved in oocyte maturation.,similarity:Belongs to the ADIPOR family.,subcellular location:Colocalizes with a lysosomal protein cathepsin D.,tissue specificity:Expressed in brain and spinal cord.,

Function：function:Steroid membrane receptor. Binds progesterone. May be involved in oocyte maturation.,similarity:Belongs to the ADIPOR family.,subcellular location:Colocalizes with a lysosomal protein cathepsin D.,tissue specificity:Expressed in brain and spinal cord.,

Subcellular Location：Cell membrane ; Multi-pass membrane protein . Colocalizes with a lysosomal protein CTSD/cathepsin D. .

Expression：Highly expressed in the hypothalamus (PubMed:23161870). Also expressed in spinal cord, kidney and testis.