Target:MOT2
Gene Name:SLC16A7 MCT2
Protein Name:Monocarboxylate transporter 2 (MCT 2) (Solute carrier family 16 member 7)
Human Gene Id:9194
Human Swiss Prot No:O60669
Mouse Swiss Prot No:O70451
Rat Swiss Prot No:Q63344
Immunogen:Synthesized peptide derived from human protein . at AA range: 220-300
Specificity:MOT2 Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):52kD
Background: This gene is a member of the monocarboxylate transporter family. Members in this family transport metabolites, such as lactate, pyruvate, and ketone bodies. The protein encoded by this gene catalyzes the proton-linked transport of monocarboxylates and has the highest affinity for pyruvate. This protein has been reported to be more highly expressed in prostate and colorectal cancer specimens when compared to control specimens. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012],
Subcellular Location:Cell membrane ; Multi-pass membrane protein .
Expression:Detected in heart and in blood lymphocytes and monocytes (at protein level). High expression in testis, moderate to low in spleen, heart, kidney, pancreas, skeletal muscle, brain and Leukocyte. Restricted expression in normal tissues, but widely expressed in cancer cells.