Target:Mos
Fields:Oocyte meiosis;Regulation of actin cytoskeleton;Progesterone-mediated oocyte maturation
Gene Name:MOS
Protein Name:Proto-oncogene serine/threonine-protein kinase mos
Human Gene Id:4342
Human Swiss Prot No:P00540
Mouse Swiss Prot No:P00536
Immunogen:The antiserum was produced against synthesized peptide derived from human MOS. AA range:61-110
Specificity:Mos Polyclonal Antibody detects endogenous levels of Mos protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:MOS;Proto-oncogene serine/threonine-protein kinase mos;Oocyte maturation factor mos;Proto-oncogene c-Mos
Observed Band(KD):40kD
Background: MOS is a serine/threonine kinase that activates the MAP kinase cascade through direct phosphorylation of the MAP kinase activator MEK (MAP2K1; MIM 176872) (Prasad et al., 2008 [PubMed 18246541]).[supplied by OMIM, Jul 2009],
Function:catalytic activity:ATP + a protein = ADP + a phosphoprotein.,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,tissue specificity:Expressed specifically in testis during spermatogenesis.,
Subcellular Location:intracellular,
Expression:Expressed specifically in testis during spermatogenesis.