Target：MOF

Gene Name：KAT8

Protein Name：Histone acetyltransferase KAT8

Human Gene Id：84148

Human Swiss Prot No：Q9H7Z6

Mouse Gene Id：67773

Mouse Swiss Prot No：Q9D1P2

Rat Gene Id：310194

Rat Swiss Prot No：Q5XI06

Immunogen：The antiserum was produced against synthesized peptide derived from human MYST1. AA range:101-150

Specificity：MOF Polyclonal Antibody detects endogenous levels of MOF protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：KAT8;MOF;MYST1;PP7073;Histone acetyltransferase KAT8;Lysine acetyltransferase 8;MOZ; YBF2/SAS3, SAS2 and TIP60 protein 1;MYST-1;hMOF

Molecular Weight(Da)：52kD

Background： This gene encodes a member of the MYST histone acetylase protein family. The encoded protein has a characteristic MYST domain containing an acetyl-CoA-binding site, a chromodomain typical of proteins which bind histones, and a C2HC-type zinc finger. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012],

Function：catalytic activity:Acetyl-CoA + histone = CoA + acetylhistone.,function:Histone acetyltransferase which may be involved in transcriptional activation. May influence the function of ATM.,similarity:Belongs to the MYST (SAS/MOZ) family.,similarity:Contains 1 C2HC-type zinc finger.,similarity:Contains 1 chromo domain.,subunit:Component of a multisubunit histone acetyltransferase complex (MSL) at least composed of the MOF/MYST1, MSL1/hampin, MSL2L1 and MSL3L1. Interacts with the chromodomain of MORF4L1/MRG15. Interacts with ATM through the chromodomain.,

Subcellular Location：Nucleus . Chromosome .

Expression： Brain,Embryo,Heart,Uterus,