Target:ODC
Gene Name:SLC25A21
Protein Name:Mitochondrial 2-oxodicarboxylate carrier
Human Gene Id:89874
Human Swiss Prot No:Q9BQT8
Mouse Gene Id:217593
Mouse Swiss Prot No:Q8BZ09
Rat Gene Id:171151
Rat Swiss Prot No:Q99JD3
Immunogen:The antiserum was produced against synthesized peptide derived from human SLC25A21. AA range:134-183
Specificity:ODC Polyclonal Antibody detects endogenous levels of ODC protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:SLC25A21;ODC;Mitochondrial 2-oxodicarboxylate carrier;Solute carrier family 25 member 21
Observed Band(KD):36kD
Background: SLC25A21 is a homolog of the S. cerevisiae ODC proteins, mitochondrial carriers that transport C5-C7 oxodicarboxylates across inner mitochondrial membranes. One of the species transported by ODC is 2-oxoadipate, a common intermediate in the catabolism of lysine, tryptophan, and hydroxylysine in mammals. Within mitochondria, 2-oxoadipate is converted into acetyl-CoA.[supplied by OMIM, Apr 2004],
Function:function:Transports C5-C7 oxodicarboxylates across the inner membranes of mitochondria. Can transport 2-oxoadipate, 2-oxoglutarate, adipate, glutarate, and to a lesser extent, pimelate, 2-oxopimelate, 2-aminoadipate, oxaloacetate, and citrate.,similarity:Belongs to the mitochondrial carrier family.,similarity:Contains 3 Solcar repeats.,tissue specificity:Ubiquitous.,
Subcellular Location:Mitochondrion inner membrane; Multi-pass membrane protein.
Expression:Expressed in placenta, gall bladder and colon.