Target:OATP1
Fields:Bile secretion
Gene Name:SLCO1A2
Protein Name:Solute carrier organic anion transporter family member 1A2
Human Gene Id:6579
Human Swiss Prot No:P46721
Immunogen:The antiserum was produced against synthesized peptide derived from human SLCO1A2. AA range:251-300
Specificity:OATP1 Polyclonal Antibody detects endogenous levels of OATP1 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:SLCO1A2;OATP;OATP1;OATP1A2;SLC21A3;Solute carrier organic anion transporter family member 1A2;OATP-A;Organic anion-transporting polypeptide 1;OATP-1;Sodium-independent organic anion transporter;Solute carrier family 21 member 3
Observed Band(KD):80kD
Background: This gene encodes a sodium-independent transporter which mediates cellular uptake of organic ions in the liver. Its substrates include bile acids, bromosulphophthalein, and some steroidal compounds. The protein is a member of the SLC21A family of solute carriers. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2008],
Function:function:Mediates the Na(+)-independent transport of organic anions such as sulfobromophthalein (BSP) and conjugated (taurocholate) and unconjugated (cholate) bile acids.,similarity:Belongs to the organo anion transporter (TC 2.A.60) family.,
Subcellular Location:Cell membrane; Multi-pass membrane protein.
Expression: Brain,Liver,Teratocarcinoma,