Target:NUDC3
Gene Name:NUDCD3 KIAA1068
Protein Name:NudC domain-containing protein 3
Human Gene Id:23386
Human Swiss Prot No:Q8IVD9
Mouse Swiss Prot No:Q8R1N4
Immunogen:Synthesized peptide derived from human protein . at AA range: 30-110
Specificity:NUDC3 Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):39kD
Background: The product of this gene functions to maintain the stability of dynein intermediate chain. Depletion of this gene product results in aggregation and degradation of dynein intermediate chain, mislocalization of the dynein complex from kinetochores, spindle microtubules, and spindle poles, and loss of gamma-tubulin from spindle poles. The protein localizes to the Golgi apparatus during interphase, and levels of the protein increase after the G1/S transition. [provided by RefSeq, Jul 2008],
Function:PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 CS domain.,
Subcellular Location:cytoplasm,
Expression: Brain,Epithelium,Pancreas,Placenta,