Target：Ribosomal Protein L22

Fields：Ribosome;Coronavirus disease - COVID-19

Gene Name：RPL22

Protein Name：60S ribosomal protein L22

Human Gene Id：6146

Human Swiss Prot No：P35268

Mouse Gene Id：1.00505e+008

Mouse Swiss Prot No：P67984

Rat Gene Id：81768

Rat Swiss Prot No：P47198

Immunogen：The antiserum was produced against synthesized peptide derived from human RPL22. AA range:51-100

Specificity：Ribosomal Protein L22 Polyclonal Antibody detects endogenous levels of Ribosomal Protein L22 protein.

Formulation：Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Other Name：RPL22;60S ribosomal protein L22;EBER-associated protein;EAP;Epstein-Barr virus small RNA-associated protein;Heparin-binding protein HBp15

Molecular Weight(Da)：15kD

Background： Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 60S subunit. The protein belongs to the L22E family of ribosomal proteins. Its initiating methionine residue is post-translationally removed. The protein can bind specifically to Epstein-Barr virus-encoded RNAs (EBERs) 1 and 2. The mouse protein has been shown to be capable of binding to heparin. Transcript variants utilizing alternative polyA signals exist. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. It was previously thought that this gene mapped to 3q26 and that it was fused to the acute myeloid leukemia 1 (AML1

Function：miscellaneous:Binds to Epstein-Barr virus small RNAs and to heparin.,similarity:Belongs to the ribosomal protein L22e family.,

Subcellular Location：nucleus,cytoplasm,cytosol,ribosome,focal adhesion,cytosolic large ribosomal subunit,intracellular ribonucleoprotein complex,extracellular matrix,extracellular exosome,

Expression： Brain,Cervix,Cervix carcinoma,Eye,Placenta,Submandibular gland,