Target:Ribosomal Protein L14
Fields:Ribosome;Coronavirus disease - COVID-19
Gene Name:RPL14
Protein Name:60S ribosomal protein L14
Human Gene Id:9045
Human Swiss Prot No:P50914
Mouse Gene Id:67115
Mouse Swiss Prot No:Q9CR57
Rat Swiss Prot No:Q63507
Immunogen:The antiserum was produced against synthesized peptide derived from human RPL14. AA range:71-120
Specificity:Ribosomal Protein L14 Polyclonal Antibody detects endogenous levels of Ribosomal Protein L14 protein.
Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Other Name:RPL14;60S ribosomal protein L14;CAG-ISL 7
Observed Band(KD):26kD
Background: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L14E family of ribosomal proteins. It contains a basic region-leucine zipper (bZIP)-like domain. The protein is located in the cytoplasm. This gene contains a trinucleotide (GCT) repeat tract whose length is highly polymorphic; these triplet repeats result in a stretch of alanine residues in the encoded protein. Transcript variants utilizing alternative polyA signals and alternative 5'-terminal exons exist but all encode the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Function:polymorphism:The poly-Ala stretch is highly polymorphic.,similarity:Belongs to the ribosomal protein L14e family.,
Subcellular Location:cytoplasm,cytosol,ribosome,cell-cell adherens junction,membrane,cytosolic large ribosomal subunit,extracellular exosome,
Expression: Brain,Cervix carcinoma,Dermoid cancer,Epithelium,Kidney,Muscle,Ovary,Pancreas,Skin,