Target：NU205

Fields：Nucleocytoplasmic transport;Amyotrophic lateral sclerosis

Gene Name：NUP205 C7orf14 KIAA0225

Protein Name：Nuclear pore complex protein Nup205 (205 kDa nucleoporin) (Nucleoporin Nup205)

Human Gene Id：23165

Human Swiss Prot No：Q92621

Immunogen：Synthesized peptide derived from human protein . at AA range: 240-320

Specificity：NU205 Polyclonal Antibody detects endogenous levels of protein.

Formulation：Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Source：Polyclonal, Rabbit,IgG

Dilution：WB 1:500-2000 ELISA 1:5000-20000

Purification：The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration：1 mg/ml

Storage Stability：-15°C to -25°C/1 year(Do not lower than -25°C)

Observed Band(KD)：221kD

Background：nucleoporin 205(NUP205) Homo sapiens This gene encodes a nucleoporin, which is a subunit of the nuclear pore complex that functions in active transport of proteins, RNAs and ribonucleoprotein particles between the nucleus and cytoplasm. Mutations in this gene are associated with steroid-resistant nephrotic syndrome. [provided by RefSeq, Jul 2016],

Function：subunit:Interacts with NUP93 and NUP35/NUP53.,

Subcellular Location：Nucleus membrane ; Peripheral membrane protein . Nucleus, nuclear pore complex . Localized near the center, on both the cytoplasmic and nuclear side, of the NPC core structure. .

Expression： Bone marrow,Breast,Clones donated by Kazusa DNA Research Inst.,Eye,Placenta,Pooled,Skin,