Target:OX2R
Fields:Neuroactive ligand-receptor interaction
Gene Name:HCRTR2
Protein Name:Orexin receptor type 2 (Ox-2-R) (Ox2-R) (Ox2R) (Hypocretin receptor type 2)
Human Gene Id:3062
Human Swiss Prot No:O43614
Mouse Swiss Prot No:P58308
Rat Swiss Prot No:P56719
Immunogen:Synthesized peptide derived from human protein . at AA range: 280-360
Specificity:OX2R Polyclonal Antibody detects endogenous levels of protein.
Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Source:Polyclonal, Rabbit,IgG
Dilution:WB 1:500-2000 ELISA 1:5000-20000
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:1 mg/ml
Storage Stability:-15°C to -25°C/1 year(Do not lower than -25°C)
Observed Band(KD):48kD
Background: The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein binds the hypothalamic neuropeptides orexin A and orexin B. A related gene (HCRTR1) encodes a G-protein coupled receptor that selectively binds orexin A. [provided by RefSeq, Jan 2009],
Function:function:Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides.,similarity:Belongs to the G-protein coupled receptor 1 family.,
Subcellular Location:Cell membrane ; Multi-pass membrane protein .
Expression: Cerebellum,